Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	3234
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Oprm1
Name:	opioid receptor, mu 1

Acc ID:	CHEBI:80156
Term:	Endomorphin-1
Definition:	null
Chemical ID:	MESH:C105293

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Oprm1	affects activity	ISO	RGD:1551432	6480464	CTD	endomorphin 1 affects the activity of OPRM1 protein	PMID:11726782
Oprm1	multiple interactions	ISO	RGD:1551432	6480464	CTD	[naloxonazine binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to endomorphin 1	PMID:11726782

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