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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730846
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP8
Name: caspase 8
Acc ID: CHEBI:80043
Term: Nodularin
Definition: An ether that has formula C41H60N8O10.
Chemical ID: MESH:C063998
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP8increases expressionEXP 6480464CTDnodularin results in increased expression of CASP8 mRNAPMID:27061667
CASP8multiple interactionsEXP 6480464CTDsauchinone inhibits the reaction [nodularin results in increased expression of CASP8 mRNA]PMID:27061667
CASP8increases activityISOCasp8 (Rattus norvegicus)6480464CTDnodularin results in increased activity of CASP8 proteinPMID:25192816
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