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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552419
Species: Mus musculus
RGD Object: Gene
Symbol: Map2k6
Name: mitogen-activated protein kinase kinase 6
Acc ID: CHEBI:80025
Term: Salinomycin
Definition: A spiroketal that has formula C42H70O11.
Chemical ID: MESH:C010327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map2k6multiple interactionsISOMAP2K6 (Homo sapiens)6480464CTD[salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP mRNA]; [salinomycin co-treated with tanespimycin] inhibits the reaction [MAP2K6 protein results in increased expression of TYMP protein]PMID:30796972
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