Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	730847
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Casp8
Name:	caspase 8

Acc ID:	CHEBI:7986
Term:	Pentoxifylline
Definition:	An oxopurine that has formula C13H18N4O3.
Chemical ID:	MESH:D010431

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Casp8	multiple interactions	ISO	CASP8 (Homo sapiens)	6480464	CTD	Pentoxifylline promotes the reaction [TNFSF10 protein results in increased activity of CASP8 protein]	PMID:20804743

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.