GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNFSF10 | increases expression | EXP | | 6480464 | CTD | Pentoxifylline results in increased expression of TNFSF10 mRNA | PMID:18851957 | TNFSF10 | multiple interactions | EXP | | 6480464 | CTD | [Pentoxifylline co-treated with TNFSF10 protein] results in decreased expression of BCL2L1 protein; [Pentoxifylline co-treated with TNFSF10 protein] results in decreased expression of BIRC2 protein; [Pentoxifylline co-treated with TNFSF10 protein] results in decreased expression of BIRC3 protein; [Pentoxifylline co-treated with TNFSF10 protein] results in decreased expression of CFLAR protein; [Pentoxifylline co-treated with TNFSF10 protein] results in decreased expression of XIAP protein; [Pentoxifylline co-treated with TNFSF10 protein] results in increased activity of CASP9 protein; Pentoxifylline promotes the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Pentoxifylline promotes the reaction [TNFSF10 protein results in increased cleavage of BID protein]; Pentoxifylline promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]; Pentoxifylline promotes the reaction [TNFSF10 protein results in increased secretion of CYCS protein] | PMID:20804743 | | ||||||||||||||||||||||
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