GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hsd11b1 | decreases activity | EXP | | 6480464 | CTD | Ziram results in decreased activity of HSD11B1 protein | PMID:26859423 | Hsd11b1 | decreases expression | EXP | | 6480464 | CTD | Ziram results in decreased expression of HSD11B1 mRNA; Ziram results in decreased expression of HSD11B1 protein | PMID:28973382 | Hsd11b1 | multiple interactions | EXP | | 6480464 | CTD | Ziram inhibits the reaction [[HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone]; Ziram inhibits the reaction [HSD11B1 protein results in increased oxidation of NADP]; Ziram inhibits the reaction [HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] | PMID:26859423 | | ||||||||||||||||||||||
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