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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733916
Species: Mus musculus
RGD Object: Gene
Symbol: S100a8
Name: S100 calcium binding protein A8 (calgranulin A)
Acc ID: CHEBI:7959
Term: D-penicillamine
Definition: An optically active form of penicillamine having D-configuration. Pharmaceutical form (L-form is toxic) of chelating agent used to treat heavy metal poisoning.
Chemical ID: MESH:D010396
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S100a8decreases expressionISOS100a8 (Rattus norvegicus)6480464CTDPenicillamine results in decreased expression of S100A8 mRNAPMID:19575532
S100a8increases expressionISOS100a8 (Rattus norvegicus)6480464CTDPenicillamine results in increased expression of S100A8 mRNAPMID:19575532
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