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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69093
Species: Homo sapiens
RGD Object: Gene
Symbol: HNF4A
Name: hepatocyte nuclear factor 4 alpha
Acc ID: CHEBI:79516
Term: Nonylphenol
Definition: null
Chemical ID: MESH:C025256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HNF4Amultiple interactionsEXP 6480464CTDAHR protein affects the reaction [nonylphenol results in decreased expression of and results in decreased acetylation of HNF4A protein]; HDAC2 protein affects the reaction [nonylphenol results in decreased expression of and results in decreased acetylation of HNF4A protein]; HNF4A protein inhibits the reaction [nonylphenol results in decreased expression of TNFSF15 mRNA]; HNF4A protein inhibits the reaction [nonylphenol results in increased expression of PECAM1 protein]; nonylphenol results in decreased expression of and results in decreased acetylation of HNF4A proteinPMID:34974051
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