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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3213
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ntrk2
Name: neurotrophic receptor tyrosine kinase 2
Acc ID: CHEBI:79516
Term: Nonylphenol
Definition: null
Chemical ID: MESH:C025256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ntrk2decreases expressionEXP 6480464CTDnonylphenol results in decreased expression of NTRK2 mRNA; nonylphenol results in decreased expression of NTRK2 protein; nonylphenol results in decreased expression of NTRK2 protein modified formPMID:35662570
Ntrk2decreases expressionISONtrk2 (Mus musculus)6480464CTDnonylphenol results in decreased expression of NTRK2 protein modified formPMID:35662570
Ntrk2multiple interactionsISONtrk2 (Mus musculus)6480464CTD[BDNF protein results in decreased susceptibility to nonylphenol] which results in increased expression of NTRK2 protein; BDNF protein inhibits the reaction [nonylphenol results in decreased expression of NTRK2 protein modified form]PMID:35662570
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