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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2901
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: CHEBI:7940
Term: patchouli alcohol
Definition: A carbotricyclic compound and sesquiterpenoid tertiary alcohol that is tricyclo[5.3.1.0(3,8)]undecan-3-ol which is substituted at positions 2, 2, 6 and 8 by methyl groups (the 1R,3R,6S,7S,8S-diastereoisomer).
Chemical ID: MESH:C052983
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6multiple interactionsEXP 6480464CTDpatchouli alcohol inhibits the reaction [Ethanol results in increased expression of IL6 protein]

PMID:25168850
Il6multiple interactionsISORGD:108026480464CTDpatchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] patchouli alcohol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]

PMID:23348408
Il6multiple interactionsISORGD:13525826480464CTDpatchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] patchouli alcohol inhibits the reaction [TNF protein results in increased expression of IL6 protein]

PMID:23348408
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