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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733969
Species: Mus musculus
RGD Object: Gene
Symbol: Ikbkb
Name: inhibitor of kappaB kinase beta
Acc ID: CHEBI:7939
Term: parthenolide
Definition: A sesquiterpene lactone and active principle of Feverfew (Tanacetum parthenium).
Chemical ID: MESH:C002669
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ikbkbmultiple interactionsISOIKBKB (Homo sapiens)6480464CTDparthenolide inhibits the reaction [Simvastatin results in increased phosphorylation of IKBKB protein]PMID:18463201
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