Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	3889
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Tp53
Name:	tumor protein p53

Acc ID:	CHEBI:7939
Term:	parthenolide
Definition:	A sesquiterpene lactone and active principle of Feverfew (Tanacetum parthenium).
Chemical ID:	MESH:C002669

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Tp53	increases expression	ISO	TP53 (Homo sapiens)	6480464	CTD	parthenolide results in increased expression of TP53 protein	PMID:16024633

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.