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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1586174
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sat1
Name: spermidine/spermine N1-acetyl transferase 1
Acc ID: CHEBI:79369
Term: elesclomol
Definition: A carbohydrazide obtained by formal condensation of the carboxy groups of malonic acid with the hydrino groups of two molar equivalents of N-methylbenzenecarbothiohydrazide
Chemical ID: MESH:C512195
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sat1increases expressionISORGD:13463236480464CTDelesclomol results in increased expression of SAT1 mRNA

PMID:18723479
Sat1multiple interactionsISORGD:13463236480464CTDAcetylcysteine inhibits the reaction [elesclomol results in increased expression of SAT1 mRNA]

PMID:18723479
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