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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: CHEBI:7931
Term: paricalcitol
Definition: A seco-cholestane that has formula C27H44O3.
Chemical ID: MESH:C084656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb1decreases expressionEXP 6480464CTDparicalcitol results in decreased expression of TGFB1 mRNA; paricalcitol results in decreased expression of TGFB1 proteinPMID:17513326
Tgfb1multiple interactionsEXP 6480464CTDEnalapril promotes the reaction [paricalcitol results in decreased expression of TGFB1 mRNA]; Enalapril promotes the reaction [paricalcitol results in decreased expression of TGFB1 protein]PMID:17513326
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