GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ABCC3 | affects transport | EXP | | 6480464 | CTD | ABCC3 protein affects the transport of estradiol-17 beta-glucuronide | PMID:12704183 | ABCC3 | increases activity | EXP | | 6480464 | CTD | estradiol-17 beta-glucuronide results in increased activity of ABCC3 protein | PMID:17569508 | ABCC3 | increases transport | EXP | | 6480464 | CTD | ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide | PMID:19114588 | ABCC3 | multiple interactions | EXP | | 6480464 | CTD | Bile Acids and Salts inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; Ethinyl Estradiol metabolite promotes the reaction [ABCC3 protein results in increased uptake of estradiol-17 beta-glucuronide]; Furosemide inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; Indomethacin inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; Probenecid inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; resveratrol metabolite promotes the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]; resveratrol-4'-O-glucuronide inhibits the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide] | PMID:12704183 PMID:14722317 PMID:19114588 | |
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