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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736060
Species: Homo sapiens
RGD Object: Gene
Symbol: GSTM1
Name: glutathione S-transferase mu 1
Acc ID: CHEBI:78886
Term: 2-tert-butylhydroquinone
Definition: A member of the class of hydroquinones in which one of the ring hydrogens of hydroquinone is replaced by a tert-butyl group.
Chemical ID: MESH:C018855
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSTM1increases expressionEXP 6480464CTD2-tert-butylhydroquinone results in increased expression of GSTM1 proteinPMID:21443188
GSTM1increases expressionISOGstm1 (Mus musculus)6480464CTD2-tert-butylhydroquinone results in increased expression of GSTM1 mRNAPMID:32428544
GSTM1multiple interactionsISOGstm1 (Mus musculus)6480464CTD[2-tert-butylhydroquinone co-treated with Cisplatin] results in increased expression of GSTM1 mRNAPMID:32428544
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