GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp9 | multiple interactions | EXP | | 6480464 | CTD | [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein] | PMID:20920558 PMID:22085843 | Casp9 | increases activity | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | pyrrolidine dithiocarbamic acid results in increased activity of CASP9 protein | PMID:12198114 | | ||||||||||||||||||||||
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