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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1598328
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ngf
Name: nerve growth factor
Acc ID: CHEBI:78741
Term: oxidopamine
Definition: A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Chemical ID: MESH:D016627
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ngfdecreases expressionISONgf (Mus musculus)6480464CTDOxidopamine results in decreased expression of NGF proteinPMID:29054324
Ngfmultiple interactionsISONgf (Mus musculus)6480464CTDchrysin inhibits the reaction [Oxidopamine results in decreased expression of NGF protein]PMID:29054324
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