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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62288
Species: Mus musculus
RGD Object: Gene
Symbol: F2
Name: coagulation factor II
Acc ID: CHEBI:78734
Term: tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate
Definition: A tropane alkaloid that is (1R,5)-8-methyl-8-azabicyclo[3.2.1]octane substituted by a (3-hydroxy-2-phenylpropanoyl)oxy group at position 3.
Chemical ID: MESH:D001285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F2multiple interactionsEXP 6480464CTD[Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in decreased expression of F2 mRNA; [Paraoxon co-treated with Atropine co-treated with Obidoxime Chloride] results in increased activity of F2 proteinPMID:30515700
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