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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732474
Species: Mus musculus
RGD Object: Gene
Symbol: Grb2
Name: growth factor receptor bound protein 2
Acc ID: CHEBI:78708
Term: Nonidet P-40
Definition: A poly(ether) macromolecule that is polyethylene glycol in which one of the terminal hydroxy groups has been converted to the corresponding p-octylphenyl ether. A nonionic, non-denaturing detergent, it is used for solubilising membrane proteins during isolation of membrane-protein complexes. n ~ 8.
Chemical ID: MESH:C010615
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7324736480464CTDNonidet P-40 results in decreased expression of GRB2 mRNA

PMID:26552463
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.