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RGD ID: 1350637
Species: Homo sapiens
RGD Object: Gene
Symbol: TOP2B
Name: DNA topoisomerase II beta
Acc ID: CHEBI:78576
Term: aflatoxin M1
Definition: A member of the class of aflatoxins that is aflatoxin B1 in which the hydrogen at position 9a is replaced by a hydroxy group.
Chemical ID: MESH:D016607
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TOP2Bdecreases expressionEXP 6480464CTDAflatoxin M1 results in decreased expression of TOP2B mRNA

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.