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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10325
Species: Mus musculus
RGD Object: Gene
Symbol: Cebpa
Name: CCAAT/enhancer binding protein alpha
Acc ID: CHEBI:78492
Term: diallyl trisulfide
Definition: An organic trisulfide that is trisulfane in which both of the hydrogens are replaced by allyl groups. A component of the essential oil of garlic and a major component of the traditional Chinese medicine allitridium, it exhibits antifungal, antitumour and antioxidant activity
Chemical ID: MESH:C042577
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpadecreases expressionEXP 6480464CTDdiallyl trisulfide results in decreased expression of CEBPA mRNA; diallyl trisulfide results in decreased expression of CEBPA proteinPMID:22137902
Cebpamultiple interactionsEXP 6480464CTD[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN; [diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids; diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]PMID:22137902
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