GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pde5a | decreases expression | EXP | | 6480464 | CTD | icariin results in decreased expression of PDE5A mRNA alternative form | PMID:17120748 | Pde5a | decreases activity | ISO | PDE5A (Homo sapiens) | 6480464 | CTD | icariin analog results in decreased activity of PDE5A protein; icariin results in decreased activity of PDE5A protein | PMID:18778098 | |
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