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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736488
Species: Homo sapiens
RGD Object: Gene
Symbol: CCNE1
Name: cyclin E1
Acc ID: CHEBI:78320
Term: 2-hydroxypropanoic acid
Definition: A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Chemical ID: MESH:D019344
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCNE1decreases expressionEXP 6480464CTDLactic Acid results in decreased expression of CCNE1 mRNAPMID:30851411
CCNE1increases expressionEXP 6480464CTDLactic Acid results in increased expression of CCNE1 proteinPMID:36336208
CCNE1multiple interactionsEXP 6480464CTD3-methyladenine inhibits the reaction [Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCNE1 protein]]; Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCNE1 protein]; PKM protein affects the reaction [Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCNE1 protein]]PMID:36336208
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