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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10268
Species: Homo sapiens
RGD Object: Gene
Symbol: CACNA1C
Name: calcium voltage-gated channel subunit alpha1 C
Acc ID: CHEBI:78291
Term: iron dextran
Definition: Please consider adding concept for iron dextran. CAS# 9004-66-4. Thank you.
Chemical ID: MESH:D007505
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CACNA1Cmultiple interactionsEXP 6480464CTD[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein; astragaloside A inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein]; Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein]PMID:33285147
CACNA1Caffects expressionISOCacna1c (Mus musculus)6480464CTDIron-Dextran Complex affects the expression of CACNA1C proteinPMID:27095094
CACNA1Cmultiple interactionsISOCacna1c (Mus musculus)6480464CTDDiltiazem inhibits the reaction [Iron-Dextran Complex affects the expression of CACNA1C protein]; Nimodipine inhibits the reaction [Iron-Dextran Complex affects the expression of CACNA1C protein]; Verapamil inhibits the reaction [Iron-Dextran Complex affects the expression of CACNA1C protein]PMID:27095094
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