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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735983
Species: Mus musculus
RGD Object: Gene
Symbol: Mitf
Name: melanogenesis associated transcription factor
Acc ID: CHEBI:78273
Term: 9-cis-retinal
Definition: A retinal in which the double bond at position 9 has cis configuration, whilst the remaining acyclic double bonds have trans configuration.
Chemical ID: MESH:C031390
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mitfincreases expressionISOMITF (Homo sapiens)6480464CTD9-cis-retinal results in increased expression of MITF mRNAPMID:23489423
Mitfmultiple interactionsISOMITF (Homo sapiens)6480464CTDALDH1A1 mutant form inhibits the reaction [9-cis-retinal results in increased expression of MITF mRNA]PMID:23489423
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