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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69038
Species: Homo sapiens
RGD Object: Gene
Symbol: IGFBP1
Name: insulin like growth factor binding protein 1
Acc ID: CHEBI:7823
Term: oxazepam
Definition: A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a hydroxy group at position 3 and phenyl group at position 5.
Chemical ID: MESH:D010076
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IGFBP1increases expressionISOIgfbp1 (Mus musculus)6480464CTDOxazepam results in increased expression of IGFBP1 mRNA; Oxazepam results in increased expression of IGFBP1 proteinPMID:12727805 PMID:15618236
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