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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:78067
Term: tin(II) chloride (anhydrous)
Definition: An inorganic chloride that has formula Cl2Sn.
Chemical ID: MESH:C023599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmox1increases activityEXP 6480464CTDstannous chloride results in increased activity of HMOX1 protein

PMID:16959961
Hmox1multiple interactionsEXP 6480464CTD[stannous chloride results in increased activity of HMOX1 protein] which results in decreased abundance of Heme [stannous chloride results in increased activity of HMOX1 protein] which results in decreased abundance of Superoxides [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2 protein [stannous chloride results in increased activity of HMOX1 protein] which results in increased expression of BCL2L1 protein

PMID:16959961
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