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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730870
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP1A1
Name: cytochrome P450 family 1 subfamily A member 1
Acc ID: CHEBI:77986
Term: dibenziodolium
Definition: An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.
Chemical ID: MESH:C007517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP1A1multiple interactionsEXP 6480464CTDdiphenyleneiodonium inhibits the reaction [Nicotine results in increased expression of CYP1A1 mRNA]; diphenyleneiodonium inhibits the reaction [sodium arsenite promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]]PMID:26535918 PMID:34171359
CYP1A1multiple interactionsISOCyp1a1 (Rattus norvegicus)6480464CTDdiphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]PMID:26880746
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