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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730823
Species: Homo sapiens
RGD Object: Gene
Symbol: ABCB1
Name: ATP binding cassette subfamily B member 1
Acc ID: CHEBI:77986
Term: dibenziodolium
Definition: An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.
Chemical ID: MESH:C007517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCB1multiple interactionsISOAbcb1a (Rattus norvegicus)6480464CTDdiphenyleneiodonium inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; diphenyleneiodonium inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]PMID:18474546
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