GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | multiple interactions | EXP | | 6480464 | CTD | diphenyleneiodonium inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; diphenyleneiodonium inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; diphenyleneiodonium inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; diphenyleneiodonium inhibits the reaction [Silicon Dioxide analog promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; diphenyleneiodonium inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL1B protein] | PMID:19005069 PMID:24685903 PMID:27311643 | Il1b | decreases response to substance | ISO | IL1B (Homo sapiens) | 6480464 | CTD | diphenyleneiodonium results in decreased susceptibility to IL1B protein | PMID:21211511 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | diphenyleneiodonium inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; diphenyleneiodonium inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; diphenyleneiodonium inhibits the reaction [IL1B protein affects the localization of NCF1 protein]; diphenyleneiodonium inhibits the reaction [IL1B protein results in increased abundance of Reactive Oxygen Species]; diphenyleneiodonium inhibits the reaction [IL1B protein results in increased abundance of Superoxides]; diphenyleneiodonium inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; diphenyleneiodonium inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; diphenyleneiodonium inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; diphenyleneiodonium inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]; diphenyleneiodonium inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; diphenyleneiodonium inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; diphenyleneiodonium inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; diphenyleneiodonium inhibits the reaction [Uric Acid results in increased secretion of IL1B protein] | PMID:18403674 PMID:19281832 PMID:21211511 PMID:23940760 PMID:27393034 | | ||||||||||||||||||||||
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