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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68943
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cacna1h
Name: calcium voltage-gated channel subunit alpha1 H
Acc ID: CHEBI:77733
Term: 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile
Definition: A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
Chemical ID: MESH:D014700
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cacna1hdecreases expressionEXP 6480464CTDVerapamil results in decreased expression of CACNA1H mRNA; Verapamil results in decreased expression of CACNA1H proteinPMID:19791473
Cacna1hmultiple interactionsEXP 6480464CTDMevalonic Acid inhibits the reaction [Verapamil results in decreased expression of CACNA1H mRNA]; Mevalonic Acid inhibits the reaction [Verapamil results in decreased expression of CACNA1H protein]PMID:19791473
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