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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310370
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlk1
Name: tousled-like kinase 1
Acc ID: CHEBI:77565
Term: 2,3,7,8-tetrabromodibenzodioxine
Definition: An organobromine compound that is dibenzodioxine carrying four bromo substituents at positions 2, 3, 7 and 8.
Chemical ID: MESH:C066841
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13212386480464CTD2, 3, 7, 8-tetrabromodibenzo-4-dioxin results in decreased expression of TLK1 protein

PMID:27604104
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.