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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1624096
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c38
Name: cytochrome P450, family 2, subfamily c, polypeptide 38
Acc ID: CHEBI:77397
Term: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
Definition: A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Chemical ID: MESH:D015283
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c38decreases methylationISOCYP2C19 (Homo sapiens)6480464CTDCYP2C19 protein polymorphism results in decreased methylation of Citalopram; CYP2C19 protein results in decreased methylation of Citalopram analogPMID:12975335 PMID:9110356
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