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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1603713
Species: Homo sapiens
RGD Object: Gene
Symbol: KNG1
Name: kininogen 1
Acc ID: CHEBI:77363
Term: ramiprilat
Definition: A dipeptide that is the active metabolite of ramipril. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.
Chemical ID: MESH:C052549
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KNG1decreases degradationISOKng1 (Rattus norvegicus)6480464CTDramiprilat results in decreased degradation of KNG1 proteinPMID:2535056
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