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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:77319
Term: oltipraz
Definition: A 1,2-dithiole that is 3H-1,2-dithiole-3-thione substituted at positions 4 and 5 by methyl and pyrazin-2-yl groups respectively.
Chemical ID: MESH:C026209
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxmultiple interactionsISOBax (Mus musculus)6480464CTD[Lithocholic Acid co-treated with oltipraz] results in increased expression of BAX mRNAPMID:19433268
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTDoltipraz inhibits the reaction [Acetaminophen results in increased expression of BAX protein]PMID:33959992
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