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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731792
Species: Mus musculus
RGD Object: Gene
Symbol: Cdkn2b
Name: cyclin dependent kinase inhibitor 2B
Acc ID: CHEBI:77092
Term: fenbendazole
Definition: A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.
Chemical ID: MESH:D005273
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:23246480464CTDFenbendazole results in increased expression of CDKN2B mRNA

PMID:23411599
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.