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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736060
Species: Homo sapiens
RGD Object: Gene
Symbol: GSTM1
Name: glutathione S-transferase mu 1
Acc ID: CHEBI:77013
Term: beta-naphthoflavone
Definition: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
Chemical ID: MESH:D019324
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSTM1increases expressionISOGstm1 (Mus musculus)6480464CTDbeta-Naphthoflavone results in increased expression of GSTM1 mRNAPMID:18723825
GSTM1increases expressionISOGstm1 (Rattus norvegicus)6480464CTDbeta-Naphthoflavone results in increased expression of GSTM1 mRNAPMID:22687991
GSTM1multiple interactionsISOGstm1 (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]PMID:18164116 PMID:20045035
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