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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558311
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2b10
Name: cytochrome P450, family 2, subfamily b, polypeptide 10
Acc ID: CHEBI:77013
Term: beta-naphthoflavone
Definition: An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
Chemical ID: MESH:D019324
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b10multiple interactionsEXP 6480464CTD[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP2B10 mRNAPMID:19737545
Cyp2b10increases activityISOCYP2B6 (Homo sapiens)6480464CTDbeta-Naphthoflavone results in increased activity of CYP2B6 proteinPMID:19497361 PMID:22258563
Cyp2b10increases expressionISOCYP2B6 (Homo sapiens)6480464CTDbeta-Naphthoflavone results in increased expression of CYP2B6 mRNAPMID:19118567
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