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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp12
Name: caspase 12
Acc ID: CHEBI:77012
Term: methylseleninic acid
Definition: An organoselenium compound that is seleninic acid in which the hydrogen attached to selenium is replaced by a methyl group.
Chemical ID: MESH:C008493
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases cleavageISORGD:13480776480464CTDmethylselenic acid results in increased cleavage of CASP12 protein

PMID:16204082
multiple interactionsISORGD:13480776480464CTDHSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of CASP12 protein]

PMID:16204082
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.