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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2582
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Esr2
Name: estrogen receptor 2
Acc ID: CHEBI:77006
Term: 17beta-estradiol 3-benzoate
Definition: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.
Chemical ID: MESH:C074283
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Esr2affects expressionEXP 6480464CTDestradiol 3-benzoate affects the expression of ESR2 mRNAPMID:19350480
Esr2decreases expressionEXP 6480464CTDestradiol 3-benzoate results in decreased expression of ESR2; estradiol 3-benzoate results in decreased expression of ESR2 mRNAPMID:15375486 PMID:24352099
Esr2increases expressionEXP 6480464CTDestradiol 3-benzoate results in increased expression of ESR2 mRNAPMID:27830003
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