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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736649
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP8B1
Name: cytochrome P450 family 8 subfamily B member 1
Acc ID: CHEBI:76987
Term: metacetamol
Definition: A derivative of phenol which has an acetamido substituent located meta to the phenolic -OH group. It is a non-toxic regioisomer of paracetamol with analgesic properties, but has never been marketed as a drug.
Chemical ID: MESH:C026137
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP8B1decreases expressionISOCyp8b1 (Mus musculus)6480464CTD3-hydroxyacetanilide results in decreased expression of CYP8B1 mRNAPMID:18544908
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