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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3281
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pde4d
Name: phosphodiesterase 4D
Acc ID: CHEBI:76792
Term: 5-(hydroxymethyl)cytosine
Definition: A nucleobase analogue that is cytosine in which the hydrogen at position 5 is replaced by a hydroxymethyl group.
Chemical ID: MESH:C011865
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pde4dmultiple interactionsISOPde4d (Mus musculus)6480464CTD[bisphenol A results in increased methylation of PDE4D exon] which results in increased abundance of 5-hydroxymethylcytosinePMID:30044229
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