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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69298
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Enpp2
Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
Acc ID: CHEBI:76603
Term: chlorendic acid
Definition: A bridged organochlorine compound resulting from the Diels-Alder reaction of hexachlorocyclopentadiene with maleic anhydride followed by hydrolysis of the resulting anhydride. A chemical intermediate used in the preparation of fire-retardant polyester resins and plasticisers.
Chemical ID: MESH:C035377
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Enpp2increases expressionISORGD:7344096480464CTDchlorendic acid results in increased expression of ENPP2 mRNAPMID:22952646
Enpp2increases secretionISORGD:7344096480464CTDchlorendic acid results in increased secretion of ENPP2 proteinPMID:22952646
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