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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61926
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gjb1
Name: gap junction protein, beta 1
Acc ID: CHEBI:76603
Term: chlorendic acid
Definition: A bridged organochlorine compound resulting from the Diels-Alder reaction of hexachlorocyclopentadiene with maleic anhydride followed by hydrolysis of the resulting anhydride. A chemical intermediate used in the preparation of fire-retardant polyester resins and plasticisers.
Chemical ID: MESH:C035377
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gjb1multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with chlorendic acid] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with chlorendic acid] results in decreased expression of GJB1 proteinPMID:1973356
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