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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68350
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
Acc ID: CHEBI:76591
Term: (25R)-cholest-5-ene-3beta,26-diol
Definition: A 26-hydroxycholesterol in which the 25-position has R-configuration.
Chemical ID: MESH:C076996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases activityISORGD:684936480464CTD27-hydroxycholesterol results in increased activity of NR5A1 protein

PMID:9144161
multiple interactionsISORGD:684936480464CTD27-hydroxycholesterol promotes the reaction [NR5A1 protein results in increased expression of STAR protein]

PMID:9804848
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