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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619753
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smpd2
Name: sphingomyelin phosphodiesterase 2
Acc ID: CHEBI:76591
Term: (25R)-cholest-5-ene-3beta,26-diol
Definition: A 26-hydroxycholesterol in which the 25-position has R-configuration.
Chemical ID: MESH:C076996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smpd2decreases activityISOSMPD2 (Homo sapiens)6480464CTD27-hydroxycholesterol results in decreased activity of SMPD2 proteinPMID:15261762
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