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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735336
Species: Mus musculus
RGD Object: Gene
Symbol: Akt1
Name: thymoma viral proto-oncogene 1
Acc ID: CHEBI:76451
Term: alloxan
Definition: A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.
Chemical ID: MESH:D000496
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1decreases phosphorylationEXP 6480464CTDAlloxan results in decreased phosphorylation of AKT1 proteinPMID:26827782
Akt1multiple interactionsEXP 6480464CTDPhycocyanin inhibits the reaction [Alloxan results in decreased phosphorylation of AKT1 protein]PMID:26827782
Akt1decreases phosphorylationISOAkt1 (Rattus norvegicus)6480464CTDAlloxan results in decreased phosphorylation of AKT1 proteinPMID:33359794
Akt1multiple interactionsISOAkt1 (Rattus norvegicus)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rh4 inhibits the reaction [Alloxan results in decreased phosphorylation of AKT1 protein]]; ginsenoside Rh4 inhibits the reaction [Alloxan results in decreased phosphorylation of AKT1 protein]PMID:33359794
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