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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730855
Species: Homo sapiens
RGD Object: Gene
Symbol: SOD1
Name: superoxide dismutase 1
Acc ID: CHEBI:76451
Term: alloxan
Definition: A member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.
Chemical ID: MESH:D000496
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOD1affects response to substanceISOSod1 (Mus musculus)6480464CTDSOD1 protein affects the susceptibility to AlloxanPMID:18502742
SOD1decreases activityISOSod1 (Rattus norvegicus)6480464CTDAlloxan results in decreased activity of SOD1 proteinPMID:10871429
SOD1multiple interactionsISOSod1 (Rattus norvegicus)6480464CTDSulfur Dioxide inhibits the reaction [Alloxan results in decreased activity of SOD1 protein]PMID:10871429
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