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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305078
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sulf2
Name: sulfatase 2
Acc ID: CHEBI:76394
Term: 2-nitro-p-phenylenediamine
Definition: A primary amino compound that is p-phenylenediamine in which one of the hydrogens attached to the benzene ring is replaced by a nitro group. It is a cosmetic hair dye intermediate that is used in permanent hair colouring products (diluted 1:1 with an oxidising agent prior to application).
Chemical ID: MESH:C014706
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sulf2decreases expressionEXP 6480464CTD2-nitro-4-phenylenediamine results in decreased expression of SULF2 mRNAPMID:17070881
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